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Vaccine-induced ICOS(+)CD38(+) circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways

Humoral immune responses are dysregulated with aging, but the cellular and molecular pathways involved remain incompletely understood. In particular, little is known about the effects of aging on T follicular helper (Tfh) CD4 cells, the key cells that provide help to B cells for effective humoral im...

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Detalles Bibliográficos
Autores principales:	Herati, Ramin Sedaghat, Silva, Luisa Victoria, Vella, Laura A., Muselman, Alexander, Alanio, Cecile, Bengsch, Bertram, Kurupati, Raj K., Kannan, Senthil, Manne, Sasikanth, Kossenkov, Andrew V., Canaday, David H., Doyle, Susan A., Ertl, Hildegund C.J., Schmader, Kenneth E., Wherry, E. John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149371/ https://www.ncbi.nlm.nih.gov/pubmed/34095875 http://dx.doi.org/10.1016/j.xcrm.2021.100262

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