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Efficient and accurate identification of ear diseases using an ensemble deep learning model

Early detection and appropriate medical treatment are of great use for ear disease. However, a new diagnostic strategy is necessary for the absence of experts and relatively low diagnostic accuracy, in which deep learning plays an important role. This paper puts forward a mechanic learning model whi...

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Autores principales: Zeng, Xinyu, Jiang, Zifan, Luo, Wen, Li, Honggui, Li, Hongye, Li, Guo, Shi, Jingyong, Wu, Kangjie, Liu, Tong, Lin, Xing, Wang, Fusen, Li, Zhenzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149397/
https://www.ncbi.nlm.nih.gov/pubmed/34035389
http://dx.doi.org/10.1038/s41598-021-90345-w
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author Zeng, Xinyu
Jiang, Zifan
Luo, Wen
Li, Honggui
Li, Hongye
Li, Guo
Shi, Jingyong
Wu, Kangjie
Liu, Tong
Lin, Xing
Wang, Fusen
Li, Zhenzhang
author_facet Zeng, Xinyu
Jiang, Zifan
Luo, Wen
Li, Honggui
Li, Hongye
Li, Guo
Shi, Jingyong
Wu, Kangjie
Liu, Tong
Lin, Xing
Wang, Fusen
Li, Zhenzhang
author_sort Zeng, Xinyu
collection PubMed
description Early detection and appropriate medical treatment are of great use for ear disease. However, a new diagnostic strategy is necessary for the absence of experts and relatively low diagnostic accuracy, in which deep learning plays an important role. This paper puts forward a mechanic learning model which uses abundant otoscope image data gained in clinical cases to achieve an automatic diagnosis of ear diseases in real time. A total of 20,542 endoscopic images were employed to train nine common deep convolution neural networks. According to the characteristics of the eardrum and external auditory canal, eight kinds of ear diseases were classified, involving the majority of ear diseases, such as normal, Cholestestoma of the middle ear, Chronic suppurative otitis media, External auditory cana bleeding, Impacted cerumen, Otomycosis external, Secretory otitis media, Tympanic membrane calcification. After we evaluate these optimization schemes, two best performance models are selected to combine the ensemble classifiers with real-time automatic classification. Based on accuracy and training time, we choose a transferring learning model based on DensNet-BC169 and DensNet-BC1615, getting a result that each model has obvious improvement by using these two ensemble classifiers, and has an average accuracy of 95.59%. Considering the dependence of classifier performance on data size in transfer learning, we evaluate the high accuracy of the current model that can be attributed to large databases. Current studies are unparalleled regarding disease diversity and diagnostic precision. The real-time classifier trains the data under different acquisition conditions, which is suitable for real cases. According to this study, in the clinical case, the deep learning model is of great use in the early detection and remedy of ear diseases.
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spelling pubmed-81493972021-05-26 Efficient and accurate identification of ear diseases using an ensemble deep learning model Zeng, Xinyu Jiang, Zifan Luo, Wen Li, Honggui Li, Hongye Li, Guo Shi, Jingyong Wu, Kangjie Liu, Tong Lin, Xing Wang, Fusen Li, Zhenzhang Sci Rep Article Early detection and appropriate medical treatment are of great use for ear disease. However, a new diagnostic strategy is necessary for the absence of experts and relatively low diagnostic accuracy, in which deep learning plays an important role. This paper puts forward a mechanic learning model which uses abundant otoscope image data gained in clinical cases to achieve an automatic diagnosis of ear diseases in real time. A total of 20,542 endoscopic images were employed to train nine common deep convolution neural networks. According to the characteristics of the eardrum and external auditory canal, eight kinds of ear diseases were classified, involving the majority of ear diseases, such as normal, Cholestestoma of the middle ear, Chronic suppurative otitis media, External auditory cana bleeding, Impacted cerumen, Otomycosis external, Secretory otitis media, Tympanic membrane calcification. After we evaluate these optimization schemes, two best performance models are selected to combine the ensemble classifiers with real-time automatic classification. Based on accuracy and training time, we choose a transferring learning model based on DensNet-BC169 and DensNet-BC1615, getting a result that each model has obvious improvement by using these two ensemble classifiers, and has an average accuracy of 95.59%. Considering the dependence of classifier performance on data size in transfer learning, we evaluate the high accuracy of the current model that can be attributed to large databases. Current studies are unparalleled regarding disease diversity and diagnostic precision. The real-time classifier trains the data under different acquisition conditions, which is suitable for real cases. According to this study, in the clinical case, the deep learning model is of great use in the early detection and remedy of ear diseases. Nature Publishing Group UK 2021-05-25 /pmc/articles/PMC8149397/ /pubmed/34035389 http://dx.doi.org/10.1038/s41598-021-90345-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zeng, Xinyu
Jiang, Zifan
Luo, Wen
Li, Honggui
Li, Hongye
Li, Guo
Shi, Jingyong
Wu, Kangjie
Liu, Tong
Lin, Xing
Wang, Fusen
Li, Zhenzhang
Efficient and accurate identification of ear diseases using an ensemble deep learning model
title Efficient and accurate identification of ear diseases using an ensemble deep learning model
title_full Efficient and accurate identification of ear diseases using an ensemble deep learning model
title_fullStr Efficient and accurate identification of ear diseases using an ensemble deep learning model
title_full_unstemmed Efficient and accurate identification of ear diseases using an ensemble deep learning model
title_short Efficient and accurate identification of ear diseases using an ensemble deep learning model
title_sort efficient and accurate identification of ear diseases using an ensemble deep learning model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149397/
https://www.ncbi.nlm.nih.gov/pubmed/34035389
http://dx.doi.org/10.1038/s41598-021-90345-w
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