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Single-cell analysis of pancreatic ductal adenocarcinoma identifies a novel fibroblast subtype associated with poor prognosis but better immunotherapy response

The current pathological and molecular classification of pancreatic ductal adenocarcinoma (PDAC) provides limited guidance for treatment options, especially for immunotherapy. Cancer-associated fibroblasts (CAFs) are major players of desmoplastic stroma in PDAC, modulating tumor progression and ther...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Liang, Yiyi, Xu, Haiyan, Zhang, Xiao, Mao, Tiebo, Cui, Jiujie, Yao, Jiayu, Wang, Yongchao, Jiao, Feng, Xiao, Xiuying, Hu, Jiong, Xia, Qing, Zhang, Xiaofei, Wang, Xujun, Sun, Yongwei, Fu, Deliang, Shen, Lei, Xu, Xiaojiang, Xue, Jing, Wang, Liwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149399/ https://www.ncbi.nlm.nih.gov/pubmed/34035226 http://dx.doi.org/10.1038/s41421-021-00271-4

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