Caerulomycin and collismycin antibiotics share a trans-acting flavoprotein-dependent assembly line for 2,2’-bipyridine formation

Linear nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs) template the modular biosynthesis of numerous nonribosomal peptides, polyketides and their hybrids through assembly line chemistry. This chemistry can be complex and highly varied, and thus challenges our understanding i...

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Detalles Bibliográficos
Autores principales: Pang, Bo, Liao, Rijing, Tang, Zhijun, Guo, Shengjie, Wu, Zhuhua, Liu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149447/
https://www.ncbi.nlm.nih.gov/pubmed/34035275
http://dx.doi.org/10.1038/s41467-021-23475-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149447/
https://www.ncbi.nlm.nih.gov/pubmed/34035275
http://dx.doi.org/10.1038/s41467-021-23475-4

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