Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture

Three-dimensional models are considered a powerful tool for improving the concordance between in vitro and in vivo phenotypes. However, the duration of spheroid culture may influence the degree of correlation between these counterparts. When using immortalised cell lines as model systems, the assump...

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Detalles Bibliográficos
Autores principales: Ellero, Andrea Antonio, van den Bout, Iman, Vlok, Maré, Cromarty, Allan Duncan, Hurrell, Tracey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149451/
https://www.ncbi.nlm.nih.gov/pubmed/34035320
http://dx.doi.org/10.1038/s41598-021-89907-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149451/
https://www.ncbi.nlm.nih.gov/pubmed/34035320
http://dx.doi.org/10.1038/s41598-021-89907-9

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