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Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture
Three-dimensional models are considered a powerful tool for improving the concordance between in vitro and in vivo phenotypes. However, the duration of spheroid culture may influence the degree of correlation between these counterparts. When using immortalised cell lines as model systems, the assump...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149451/ https://www.ncbi.nlm.nih.gov/pubmed/34035320 http://dx.doi.org/10.1038/s41598-021-89907-9 |