PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis

Vanderplow et al.(1) report decreased PFC Akt-mTOR signaling in males with bipolar disorder (BD) without psychosis compared with those with psychosis, possibly related to cognitive deficits. Understanding how cognition differs between these BD subtypes clinically and biologically remains a challenge...

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Detalles Bibliográficos
Autores principales: Radulovic, Jelena, Gabbay, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149463/
https://www.ncbi.nlm.nih.gov/pubmed/34095884
http://dx.doi.org/10.1016/j.xcrm.2021.100282
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author Radulovic, Jelena
Gabbay, Vilma
author_facet Radulovic, Jelena
Gabbay, Vilma
author_sort Radulovic, Jelena
collection PubMed
description Vanderplow et al.(1) report decreased PFC Akt-mTOR signaling in males with bipolar disorder (BD) without psychosis compared with those with psychosis, possibly related to cognitive deficits. Understanding how cognition differs between these BD subtypes clinically and biologically remains a challenge.
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spelling pubmed-81494632021-06-03 PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis Radulovic, Jelena Gabbay, Vilma Cell Rep Med Preview Vanderplow et al.(1) report decreased PFC Akt-mTOR signaling in males with bipolar disorder (BD) without psychosis compared with those with psychosis, possibly related to cognitive deficits. Understanding how cognition differs between these BD subtypes clinically and biologically remains a challenge. Elsevier 2021-05-18 /pmc/articles/PMC8149463/ /pubmed/34095884 http://dx.doi.org/10.1016/j.xcrm.2021.100282 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Radulovic, Jelena
Gabbay, Vilma
PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
title PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
title_full PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
title_fullStr PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
title_full_unstemmed PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
title_short PFC mTOR signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
title_sort pfc mtor signaling as a biological signature for cognitive deficits in bipolar disorder without psychosis
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149463/
https://www.ncbi.nlm.nih.gov/pubmed/34095884
http://dx.doi.org/10.1016/j.xcrm.2021.100282
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