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β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice
Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects, limiting their long-term usage. Here, we employ a bioinformatics screen to identify drugs for repurposing as anxiolytics. Comparison of drug-...
Autores principales: | Panayotis, Nicolas, Freund, Philip A., Marvaldi, Letizia, Shalit, Tali, Brandis, Alexander, Mehlman, Tevie, Tsoory, Michael M., Fainzilber, Mike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149471/ https://www.ncbi.nlm.nih.gov/pubmed/34095883 http://dx.doi.org/10.1016/j.xcrm.2021.100281 |
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