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Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis

Lysergic acid diethylamide (LSD) is a classic psychedelic substance that is used recreationally and investigated in psychiatric research. There are no pharmacogenetic studies on LSD. In vitro metabolic studies indicate that several cytochrome P450 (CYP) isoforms (e.g., CYP2D6, CYP1A2, and CYP2C9) ar...

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Detalles Bibliográficos
Autores principales:	Vizeli, Patrick, Straumann, Isabelle, Holze, Friederike, Schmid, Yasmin, Dolder, Patrick C., Liechti, Matthias E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149637/ https://www.ncbi.nlm.nih.gov/pubmed/34035391 http://dx.doi.org/10.1038/s41598-021-90343-y

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