A combined approach for single-cell mRNA and intracellular protein expression analysis

Combined measurements of mRNA and protein expression in single cells enable in-depth analysis of cellular states. We present SPARC, an approach that combines single-cell RNA-sequencing with proximity extension essays to simultaneously measure global mRNA and 89 intracellular proteins in individual c...

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Detalles Bibliográficos
Autores principales: Reimegård, Johan, Tarbier, Marcel, Danielsson, Marcus, Schuster, Jens, Baskaran, Sathishkumar, Panagiotou, Styliani, Dahl, Niklas, Friedländer, Marc R., Gallant, Caroline J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149646/
https://www.ncbi.nlm.nih.gov/pubmed/34035432
http://dx.doi.org/10.1038/s42003-021-02142-w

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