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Generation of somatic mitochondrial DNA-replaced cells for mitochondrial dysfunction treatment
Mitochondrial diseases currently have no cure regardless of whether the cause is a nuclear or mitochondrial genome mutation. Mitochondrial dysfunction notably affects a wide range of disorders in aged individuals, including neurodegenerative diseases, cancers, and even senescence. Here, we present a...
Autores principales: | Maeda, Hideki, Kami, Daisuke, Maeda, Ryotaro, Shikuma, Akira, Gojo, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149667/ https://www.ncbi.nlm.nih.gov/pubmed/34035362 http://dx.doi.org/10.1038/s41598-021-90316-1 |
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