A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

Transthyretin amyloid (ATTR) cardiomyopathy is a debilitating disease leading to heart failure and death. It is characterized by the deposition of extracellular ATTR fibrils in the myocardium. Reducing myocardial ATTR load is a therapeutic goal anticipated to translate into restored cardiac function...

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Detalles Bibliográficos
Autores principales: Michalon, Aubin, Hagenbuch, Andreas, Huy, Christian, Varela, Evita, Combaluzier, Benoit, Damy, Thibaud, Suhr, Ole B., Saraiva, Maria J., Hock, Christoph, Nitsch, Roger M., Jan Grimm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149704/
https://www.ncbi.nlm.nih.gov/pubmed/34035264
http://dx.doi.org/10.1038/s41467-021-23274-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149704/
https://www.ncbi.nlm.nih.gov/pubmed/34035264
http://dx.doi.org/10.1038/s41467-021-23274-x

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