A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

Human organogenesis remains relatively unexplored for ethical and practical reasons. Here, we report the establishment of a single-cell transcriptome atlas of the human fetal pancreas between 7 and 10 post-conceptional weeks of development. To interrogate cell–cell interactions, we describe InterCom...

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Detalles Bibliográficos
Autores principales: Gonçalves, Carla A., Larsen, Michael, Jung, Sascha, Stratmann, Johannes, Nakamura, Akiko, Leuschner, Marit, Hersemann, Lena, Keshara, Rashmiparvathi, Perlman, Signe, Lundvall, Lene, Thuesen, Lea Langhoff, Hare, Kristine Juul, Amit, Ido, Jørgensen, Anne, Kim, Yung Hae, del Sol, Antonio, Grapin-Botton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149728/
https://www.ncbi.nlm.nih.gov/pubmed/34035279
http://dx.doi.org/10.1038/s41467-021-23295-6

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