Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages

Removal of apoptotic cells by phagocytes (also called efferocytosis) is a crucial process for tissue homeostasis. Professional phagocytes express a plethora of surface receptors enabling them to sense and engulf apoptotic cells, thus avoiding persistence of dead cells and cellular debris and their c...

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Detalles Bibliográficos
Autores principales: Wanke, Florian, Gutbier, Simon, Rümmelin, Anna, Steinberg, Malte, Hughes, Lindsey D., Koenen, Mascha, Komuczki, Juliana, Regan-Komito, Daniel, Wagage, Sagie, Hesselmann, Julia, Thoma, Ralf, Brugger, Doris, Christopeit, Tony, Wang, Hayian, Point, Floriane, Hallet, Remy, Ghosh, Sourav, Rothlin, Carla V., Patsch, Christoph, Geering, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149813/
https://www.ncbi.nlm.nih.gov/pubmed/34035216
http://dx.doi.org/10.1038/s41419-021-03770-0

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