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Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions
Focal adhesions (FAs) initiate chemical and mechanical signals involved in cell polarity, migration, proliferation and differentiation. Super-resolution microscopy revealed that FAs are organized at the nanoscale into functional layers from the lower plasma membrane to the upper actin cytoskeleton....
Autores principales: | Orré, Thomas, Joly, Adrien, Karatas, Zeynep, Kastberger, Birgit, Cabriel, Clément, Böttcher, Ralph T., Lévêque-Fort, Sandrine, Sibarita, Jean-Baptiste, Fässler, Reinhard, Wehrle-Haller, Bernhard, Rossier, Olivier, Giannone, Grégory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149821/ https://www.ncbi.nlm.nih.gov/pubmed/34035280 http://dx.doi.org/10.1038/s41467-021-23372-w |
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