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Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures

Changes in the epigenetic regulation of gene expression have a central role in evolution. Here, we extensively profiled a panel of human, chimpanzee, gorilla, orangutan, and macaque lymphoblastoid cell lines (LCLs), using ChIP-seq for five histone marks, ATAC-seq and RNA-seq, further complemented wi...

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Detalles Bibliográficos
Autores principales:	García-Pérez, Raquel, Esteller-Cucala, Paula, Mas, Glòria, Lobón, Irene, Di Carlo, Valerio, Riera, Meritxell, Kuhlwilm, Martin, Navarro, Arcadi, Blancher, Antoine, Di Croce, Luciano, Gómez-Skarmeta, José Luis, Juan, David, Marquès-Bonet, Tomàs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149829/ https://www.ncbi.nlm.nih.gov/pubmed/34035253 http://dx.doi.org/10.1038/s41467-021-23397-1

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