Sulfide catabolism ameliorates hypoxic brain injury

The mammalian brain is highly vulnerable to oxygen deprivation, yet the mechanism underlying the brain’s sensitivity to hypoxia is incompletely understood. Hypoxia induces accumulation of hydrogen sulfide, a gas that inhibits mitochondrial respiration. Here, we show that, in mice, rats, and naturall...

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Detalles Bibliográficos
Autores principales: Marutani, Eizo, Morita, Masanobu, Hirai, Shuichi, Kai, Shinichi, Grange, Robert M. H., Miyazaki, Yusuke, Nagashima, Fumiaki, Traeger, Lisa, Magliocca, Aurora, Ida, Tomoaki, Matsunaga, Tetsuro, Flicker, Daniel R., Corman, Benjamin, Mori, Naohiro, Yamazaki, Yumiko, Batten, Annabelle, Li, Rebecca, Tanaka, Tomohiro, Ikeda, Takamitsu, Nakagawa, Akito, Atochin, Dmitriy N., Ihara, Hideshi, Olenchock, Benjamin A., Shen, Xinggui, Nishida, Motohiro, Hanaoka, Kenjiro, Kevil, Christopher G., Xian, Ming, Bloch, Donald B., Akaike, Takaaki, Hindle, Allyson G., Motohashi, Hozumi, Ichinose, Fumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149856/
https://www.ncbi.nlm.nih.gov/pubmed/34035265
http://dx.doi.org/10.1038/s41467-021-23363-x

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