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Expanding the Scope of Non-invasive Prenatal Testing to Detect Fetal Chromosomal Copy Number Variations

Non-invasive prenatal testing (NIPT) for common fetal trisomies is effective. However, the usefulness of cell-free DNA testing to detect other chromosomal abnormalities is poorly understood. We analyzed the positive rate at different read depths in next-generation sequencing (NGS) and identified a s...

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Detalles Bibliográficos
Autores principales:	Chen, Songchang, Zhang, Lanlan, Gao, Jiong, Li, Shuyuan, Chang, Chunxin, Chen, Yiyao, Fei, Hongjun, Zhang, Junyu, Wang, Yanlin, Huang, Hefeng, Xu, Chenming, Lu, Daru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149898/ https://www.ncbi.nlm.nih.gov/pubmed/34055879 http://dx.doi.org/10.3389/fmolb.2021.649169

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