Target identification among known drugs by deep learning from heterogeneous networks

Without foreknowledge of the complete drug target information, development of promising and affordable approaches for effective treatment of human diseases is challenging. Here, we develop deepDTnet, a deep learning methodology for new target identification and drug repurposing in a heterogeneous dr...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangxiang, Zhu, Siyi, Lu, Weiqiang, Liu, Zehui, Huang, Jin, Zhou, Yadi, Fang, Jiansong, Huang, Yin, Guo, Huimin, Li, Lang, Trapp, Bruce D., Nussinov, Ruth, Eng, Charis, Loscalzo, Joseph, Cheng, Feixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150105/
https://www.ncbi.nlm.nih.gov/pubmed/34123272
http://dx.doi.org/10.1039/c9sc04336e

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