Cargando…

Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells

Neural cell adhesion molecule (NCAM) is involved in cell multi-directional differentiation, but its role in osteoblast differentiation is still poorly understood. In the present study, we investigated whether and how NCAM regulates osteoblastic differentiation. We found that NCAM silencing inhibited...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Bin-Feng, Feng, Xiao, Gao, Yao-Xin, Jian, Shao-Qin, Liu, Shi-Rao, Wang, Mian, Xie, Yun-Fei, Wang, Lei, Feng, Zhi-Wei, Yang, Hai-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150200/ https://www.ncbi.nlm.nih.gov/pubmed/34054729 http://dx.doi.org/10.3389/fendo.2021.657953

Ejemplares similares

Astragalin Promotes Osteoblastic Differentiation in MC3T3-E1 Cells and Bone Formation in vivo
por: Liu, Li, et al.
Publicado: (2019)

LGR5 enhances the osteoblastic differentiation of MC3T3-E1 cells through the Wnt/β-catenin pathway
por: Yu, Wei, et al.
Publicado: (2021)

Aroclor 1254 induced inhibitory effects on osteoblast differentiation in murine MC3T3-E1 cells through oxidative stress
por: Chen, Yu, et al.
Publicado: (2022)

Pentraxin 3 promotes the osteoblastic differentiation of MC3T3-E1 cells through the PI3K/Akt signaling pathway
por: Liu, Yong, et al.
Publicado: (2020)

Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/β-catenin pathway
por: Zhou, Yun, et al.
Publicado: (2021)

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?
por: McGonnell, Imelda M., et al.
Publicado: (2012)

Arbutin promotes MC3T3-E1 mouse osteoblast precursor cell proliferation and differentiation via the Wnt/β-catenin signaling pathway
por: Man, Xiangji, et al.
Publicado: (2019)

Astragaloside positively regulated osteogenic differentiation of pre-osteoblast MC3T3-E1 through PI3K/Akt signaling pathway
por: Jing, Wei Bing, et al.
Publicado: (2021)

Microcystin-leucine arginine promotes colorectal cancer cell proliferation by activating the PI3K/Akt/Wnt/β-catenin pathway
por: Tang, Yaqi, et al.
Publicado: (2022)

Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation
por: Liu, Tielong, et al.
Publicado: (2015)

High glucose promotes apoptosis and autophagy of MC3T3-E1 osteoblasts
por: Zhang, Pei, et al.
Publicado: (2020)

The PI3K/Akt Pathway in Tumors of Endocrine Tissues
por: Robbins, Helen Louise, et al.
Publicado: (2016)

Canagliflozin promotes osteoblastic MC3T3-E1 differentiation via AMPK/RUNX2 and improves bone microarchitecture in type 2 diabetic mice
por: Song, Peiyang, et al.
Publicado: (2022)

Akt Activation is Required for TGF-β1-Induced Osteoblast Differentiation of MC3T3-E1 Pre-Osteoblasts
por: Suzuki, Eiichi, et al.
Publicado: (2014)

Neuroprotective Role of the PI3 Kinase/Akt Signaling Pathway in Zebrafish
por: Chen, Shuang, et al.
Publicado: (2017)

Cinnamaldehyde Inhibits the Function of Osteosarcoma by Suppressing the Wnt/β-Catenin and PI3K/Akt Signaling Pathways
por: Huang, Yanran, et al.
Publicado: (2020)

Effect of Codonopsis Radix and Polygonati Rhizoma on the regulation of the IRS1/PI3K/AKT signaling pathway in type 2 diabetic mice
por: Mao, Yong-po, et al.
Publicado: (2022)

Trifloroside Induces Bioactive Effects on Differentiation, Adhesion, Migration, and Mineralization in Pre-Osteoblast MC3T3E-1 Cells
por: Yun, Hyung-Mun, et al.
Publicado: (2022)

Gene Expression Profiling in Mouse Embryonic Stem Cells Reveals Glycogen Synthase Kinase-3-Dependent Targets of Phosphatidylinositol 3-Kinase and Wnt/β-Catenin Signaling Pathways
por: Bartman, Colleen M., et al.
Publicado: (2014)

Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells
por: Kwak, Eun Jung, et al.
Publicado: (2012)

Cytotoxicity of Titanate-Calcium Complexes to MC3T3 Osteoblast-Like Cells
por: Chen, Yen-Wei, et al.
Publicado: (2016)

N-Cadherin Negatively Regulates Osteoblast Proliferation and Survival by Antagonizing Wnt, ERK and PI3K/Akt Signalling
por: Haÿ, Eric, et al.
Publicado: (2009)

Mechanisms of Cell Adhesion Molecules in Endocrine-Related Cancers: A Concise Outlook
por: Ruan, Yongsheng, et al.
Publicado: (2022)

Liraglutide attenuates the osteoblastic differentiation of MC3T3-E1 cells by modulating AMPK/mTOR signaling
por: Hu, Xiong-Ke, et al.
Publicado: (2016)

Kaiso regulates osteoblast differentiation and mineralization via the Itga10/PI3K/AKT signaling pathway
por: Tong, Wenwen, et al.
Publicado: (2021)

Are Wnt/β-Catenin and PI3K/AKT/mTORC1 Distinct Pathways in Colorectal Cancer?
por: Prossomariti, Anna, et al.
Publicado: (2020)

Ginsenoside Re Promotes Osteoblast Differentiation in Mouse Osteoblast Precursor MC3T3-E1 Cells and a Zebrafish Model
por: Kim, Hye-Min, et al.
Publicado: (2016)

Meloxicam Inhibited the Proliferation of LPS-Stimulated Bovine Endometrial Epithelial Cells Through Wnt/β-Catenin and PI3K/AKT Pathways
por: Cui, Luying, et al.
Publicado: (2021)

Protective effect of Agrimonia pilosa polysaccharides on dexamethasone‐treated MC3T3‐E1 cells via Wnt/β‐Catenin pathway
por: Huang, Wei, et al.
Publicado: (2020)

Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells
por: Lai, Chien-Hung, et al.
Publicado: (2014)

Effect of isopsoralen on Smad7 in osteoblastic MC3T3-E1 cells
por: Zhang, Huicun, et al.
Publicado: (2017)

In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)(2) Vitamin D(3)
por: Pendleton, Elisha, et al.
Publicado: (2017)

Manganese‐12 acetate suppresses the migration, invasion, and epithelial–mesenchymal transition by inhibiting Wnt/β‐catenin and PI3K/AKT signaling pathways in breast cancer cells
por: Ju, Hongping, et al.
Publicado: (2018)

Sandblasting and fibronectin-derived peptide immobilization on titanium surface increase adhesion and differentiation of osteoblast-like cells (MC3T3-E1)
por: Pramono, Samdharu, et al.
Publicado: (2016)

Effect of autophagy on irradiation-induced damage in osteoblast-like MC3T3-E1 cells
por: Li, Rui, et al.
Publicado: (2020)

Selenium protects against LPS-induced MC3T3-E1 cells apoptosis through modulation of microRNA-155 and PI3K/Akt signaling pathways
por: Huang, Yan, et al.
Publicado: (2020)

Gene expression of MC3T3-E1 osteoblastic cells on titanium and zirconia surface
por: Gong, Soon-Hyun, et al.
Publicado: (2013)

The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation
por: Goyden, Jake, et al.
Publicado: (2015)

Effects of Scytosiphon lomentaria on osteoblastic proliferation and differentiation of MC3T3-E1 cells
por: Park, Mi Hwa, et al.
Publicado: (2016)

Capsaicin suppresses breast cancer cell viability by regulating the CDK8/PI3K/Akt/Wnt/β-catenin signaling pathway
por: Wu, Di, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u0vu7phacpp2ok9rics3c81tof