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Nasal Extracts from Patients with Alzheimer’s Disease Induce Tau Aggregates in a Cellular Model of Tau Propagation
BACKGROUND: Emerging evidence indicates that the misfolded tau protein can propagate aggregates between cells in a prion-like manner. This prion activity has been typically studied in brain extracts of patients with Alzheimer’s disease (AD), but not in the olfactory region that can be a potential bi...
Autores principales: | Pahrudin Arrozi, Aslina, Yanagisawa, Daijiro, Kato, Tomoko, Akatsu, Hiroyasu, Hashizume, Yoshio, Kaneda, Daita, Tooyama, Ikuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150252/ https://www.ncbi.nlm.nih.gov/pubmed/34113783 http://dx.doi.org/10.3233/ADR-210298 |
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