Upregulation of Chemoresistance by Mg(2+) Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells

Several anticancer drugs including cisplatin (CDDP) induce hypomagnesemia. However, it remains fully uncertain whether Mg(2+) deficiency affects chemosensitivity of cancer cells. Here, we investigated the effect of low Mg(2+) concentration (LM) on proliferation and chemosensitivity using human lung...

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Detalles Bibliográficos
Autores principales: Onuma, Saki, Manabe, Aya, Yoshino, Yuta, Matsunaga, Toshiyuki, Asai, Tomohiro, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150369/
https://www.ncbi.nlm.nih.gov/pubmed/34066059
http://dx.doi.org/10.3390/cells10051179

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