Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson’s Disease

BACKGROUND: Human induced pluripotent stem cells (hiPSCs) have been proposed as an alternative source for cell replacement therapy for Parkinson’s disease (PD) and they provide the option of using the patient’s own cells. A few studies have investigated transplantation of patient-derived dopaminergi...

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Detalles Bibliográficos
Autores principales: Shrigley, Shelby, Nilsson, Fredrik, Mattsson, Bengt, Fiorenzano, Alessandro, Mudannayake, Janitha, Bruzelius, Andreas, Ottosson, Daniella Rylander, Björklund, Anders, Hoban, Deirdre B., Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150478/
https://www.ncbi.nlm.nih.gov/pubmed/33361611
http://dx.doi.org/10.3233/JPD-202366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150478/
https://www.ncbi.nlm.nih.gov/pubmed/33361611
http://dx.doi.org/10.3233/JPD-202366

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