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Hexarelin Modulation of MAPK and PI3K/Akt Pathways in Neuro-2A Cells Inhibits Hydrogen Peroxide—Induced Apoptotic Toxicity

Hexarelin, a synthetic hexapeptide, exerts cyto-protective effects at the mitochondrial level in cardiac and skeletal muscles, both in vitro and in vivo, may also have important neuroprotective bioactivities. This study examined the inhibitory effects of hexarelin on hydrogen peroxide (H(2)O(2))-ind...

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Detalles Bibliográficos
Autores principales: Meanti, Ramona, Rizzi, Laura, Bresciani, Elena, Molteni, Laura, Locatelli, Vittorio, Coco, Silvia, Omeljaniuk, Robert John, Torsello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150489/
https://www.ncbi.nlm.nih.gov/pubmed/34066741
http://dx.doi.org/10.3390/ph14050444

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