Peripheral Markers of Vascular Endothelial Dysfunction Show Independent but Additive Relationships with Brain-Based Biomarkers in Association with Functional Impairment in Alzheimer’s Disease

BACKGROUND: Cerebrovascular dysfunction confers risk for functional decline in Alzheimer’s disease (AD), yet the clinical interplay of these two pathogenic processes is not well understood. OBJECTIVE: We utilized Alzheimer’s Disease Neuroimaging Initiative (ADNI) data to examine associations between...

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Detalles Bibliográficos
Autores principales: Drake, Jonathan D., Chambers, Alison B., Ott, Brian R., Daiello, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150492/
https://www.ncbi.nlm.nih.gov/pubmed/33720880
http://dx.doi.org/10.3233/JAD-200759

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