Profiling the structural determinants of aminoketone derivatives as hNET and hDAT reuptake inhibitors by field-based QSAR based on molecular docking

BACKGROUND: Bupropion, one of the dual norepinephrine and dopamine reuptake inhibitors (NDRIs), is an aminoketone derivative performed effect in improving cognitive function for depression. However, its therapeutic effect is unsatisfactory due to poor clinical response, and there are only few deriva...

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Detalles Bibliográficos
Autores principales: Wang, Panpan, Jing, Chenxi, Yu, Pei, Lu, Meng, Xu, Xiaobo, Pei, Qinglan, Yan, Fengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150508/
https://www.ncbi.nlm.nih.gov/pubmed/33682763
http://dx.doi.org/10.3233/THC-218024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150508/
https://www.ncbi.nlm.nih.gov/pubmed/33682763
http://dx.doi.org/10.3233/THC-218024

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