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Pharmacological Vitamin C Treatment Impedes the Growth of Endogenous Glutamine-Dependent Cancers by Targeting Glutamine Synthetase

Purpose: Glutamine synthetase (GS) is the only currently known enzyme responsible for synthesizing endogenous glutamine (Gln). GS exerts a critical role in the oncogenesis of endogenous Gln-dependent cancers, making it an attractive target for anti-tumor therapies. A mixed-function oxidation system...

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Detalles Bibliográficos
Autores principales:	Long, Yali, Qiu, Jia, Zhang, Bing, He, Peng, Shi, Xinchong, He, Qiao, Chen, Zhifeng, Shen, Wanqing, Li, Zhoulei, Zhang, Xiangsong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150514/ https://www.ncbi.nlm.nih.gov/pubmed/34054545 http://dx.doi.org/10.3389/fphar.2021.671902

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