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Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine

Bacterial infections have been treated effectively by antibiotics since the discovery of penicillin in 1928. A worldwide increase in the use of antibiotics led to the emergence of antibiotic resistant strains in almost all bacterial pathogens, which complicates the treatment of infectious diseases....

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Autores principales: Zacharias, Nicole, Löckener, Iris, Essert, Sarah M., Sib, Esther, Bierbaum, Gabriele, Kistemann, Thomas, Schreiber, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150577/
https://www.ncbi.nlm.nih.gov/pubmed/34066054
http://dx.doi.org/10.3390/antibiotics10050571
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author Zacharias, Nicole
Löckener, Iris
Essert, Sarah M.
Sib, Esther
Bierbaum, Gabriele
Kistemann, Thomas
Schreiber, Christiane
author_facet Zacharias, Nicole
Löckener, Iris
Essert, Sarah M.
Sib, Esther
Bierbaum, Gabriele
Kistemann, Thomas
Schreiber, Christiane
author_sort Zacharias, Nicole
collection PubMed
description Bacterial infections have been treated effectively by antibiotics since the discovery of penicillin in 1928. A worldwide increase in the use of antibiotics led to the emergence of antibiotic resistant strains in almost all bacterial pathogens, which complicates the treatment of infectious diseases. Antibiotic-resistant bacteria play an important role in increasing the risk associated with the usage of surface waters (e.g., irrigation, recreation) and the spread of the resistance genes. Many studies show that important pathogenic antibiotic-resistant bacteria can enter the environment by the discharge of sewage treatment plants and combined sewage overflow events. Mussels have successfully been used as bio-indicators of heavy metals, chemicals and parasites; they may also be efficient bio-indicators for viruses and bacteria. In this study an influence of the discharge of a sewage treatment plant could be shown in regard to the presence of E. coli in higher concentrations in the mussels downstream the treatment plant. Antibiotic-resistant bacteria, resistant against one or two classes of antibiotics and relevance for human health could be detected in the mussels at different sampling sites of the river Rhine. No multidrug-resistant bacteria could be isolated from the mussels, although they were found in samples of the surrounding water body.
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spelling pubmed-81505772021-05-27 Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine Zacharias, Nicole Löckener, Iris Essert, Sarah M. Sib, Esther Bierbaum, Gabriele Kistemann, Thomas Schreiber, Christiane Antibiotics (Basel) Article Bacterial infections have been treated effectively by antibiotics since the discovery of penicillin in 1928. A worldwide increase in the use of antibiotics led to the emergence of antibiotic resistant strains in almost all bacterial pathogens, which complicates the treatment of infectious diseases. Antibiotic-resistant bacteria play an important role in increasing the risk associated with the usage of surface waters (e.g., irrigation, recreation) and the spread of the resistance genes. Many studies show that important pathogenic antibiotic-resistant bacteria can enter the environment by the discharge of sewage treatment plants and combined sewage overflow events. Mussels have successfully been used as bio-indicators of heavy metals, chemicals and parasites; they may also be efficient bio-indicators for viruses and bacteria. In this study an influence of the discharge of a sewage treatment plant could be shown in regard to the presence of E. coli in higher concentrations in the mussels downstream the treatment plant. Antibiotic-resistant bacteria, resistant against one or two classes of antibiotics and relevance for human health could be detected in the mussels at different sampling sites of the river Rhine. No multidrug-resistant bacteria could be isolated from the mussels, although they were found in samples of the surrounding water body. MDPI 2021-05-12 /pmc/articles/PMC8150577/ /pubmed/34066054 http://dx.doi.org/10.3390/antibiotics10050571 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zacharias, Nicole
Löckener, Iris
Essert, Sarah M.
Sib, Esther
Bierbaum, Gabriele
Kistemann, Thomas
Schreiber, Christiane
Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine
title Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine
title_full Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine
title_fullStr Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine
title_full_unstemmed Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine
title_short Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine
title_sort antibiotic-resistant bacteria in clams—a study on mussels in the river rhine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150577/
https://www.ncbi.nlm.nih.gov/pubmed/34066054
http://dx.doi.org/10.3390/antibiotics10050571
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