Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities

Dysregulation of messenger RNA (mRNA) processing—in particular mRNA splicing—is a hallmark of cancer. Compared to normal cells, cancer cells frequently present aberrant mRNA splicing, which promotes cancer progression and treatment resistance. This hallmark provides opportunities for developing new...

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Detalles Bibliográficos
Autores principales: Blijlevens, Maxime, Li, Jing, van Beusechem, Victor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150589/
https://www.ncbi.nlm.nih.gov/pubmed/34065983
http://dx.doi.org/10.3390/ijms22105110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150589/
https://www.ncbi.nlm.nih.gov/pubmed/34065983
http://dx.doi.org/10.3390/ijms22105110

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