Gene Expression Levels of the Prolyl Hydroxylase Domain Proteins PHD1 and PHD2 but Not PHD3 Are Decreased in Primary Tumours and Correlate with Poor Prognosis of Patients with Surgically Resected Non-Small-Cell Lung Cancer

SIMPLE SUMMARY: Hypoxia correlates with poor prognosis in several cancer types, including lung cancer. Prolyl hydroxylase domain proteins (PHDs) belong to an evolutionarily conserved superfamily of dioxygenases that play a role in cell oxygen sensing and homeostasis. In this study, we evaluated PHD1...

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Autores principales: Koren, Ana, Rijavec, Matija, Krumpestar, Tomaž, Kern, Izidor, Sadikov, Aleksander, Čufer, Tanja, Korošec, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150639/
https://www.ncbi.nlm.nih.gov/pubmed/34065840
http://dx.doi.org/10.3390/cancers13102309

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