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Genetic Determinants in HLA and Cytochrome P450 Genes in the Risk of Aromatic Antiepileptic-Induced Severe Cutaneous Adverse Reactions

Adverse drug reaction (ADR) is a pressing health problem, and one of the main reasons for treatment failure with antiepileptic drugs. This has become apparent in the event of severe cutaneous adverse reactions (SCARs), which can be life-threatening. In this review, four hypotheses were identified to...

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Detalles Bibliográficos
Autores principales: Ahmed, Ali Fadhel, Sukasem, Chonlaphat, Sabbah, Majeed Arsheed, Musa, Nur Fadhlina, Mohamed Noor, Dzul Azri, Daud, Nur Aizati Athirah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150699/
https://www.ncbi.nlm.nih.gov/pubmed/34067134
http://dx.doi.org/10.3390/jpm11050383