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The Discovery of Naringenin as Endolysosomal Two-Pore Channel Inhibitor and Its Emerging Role in SARS-CoV-2 Infection
The flavonoid naringenin (Nar), present in citrus fruits and tomatoes, has been identified as a blocker of an emerging class of human intracellular channels, namely the two-pore channel (TPC) family, whose role has been established in several diseases. Indeed, Nar was shown to be effective against n...
Autores principales: | D’Amore, Antonella, Gradogna, Antonella, Palombi, Fioretta, Minicozzi, Velia, Ceccarelli, Matteo, Carpaneto, Armando, Filippini, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150892/ https://www.ncbi.nlm.nih.gov/pubmed/34067054 http://dx.doi.org/10.3390/cells10051130 |
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