Cargando…

Targeting of GLUT5 for Transporter-Mediated Drug-Delivery Is Contingent upon Substrate Hydrophilicity

Specific link between high fructose uptake and cancer development and progression highlighted fructose transporters as potential means to achieve GLUT-mediated discrimination between normal and cancer cells. The gained expression of fructose-specific transporter GLUT5 in various cancers offers a pos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nahrjou, Nazanin, Ghosh, Avik, Tanasova, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8150966/ https://www.ncbi.nlm.nih.gov/pubmed/34064801 http://dx.doi.org/10.3390/ijms22105073

Ejemplares similares

Importance of GLUT Transporters in Disease Diagnosis and Treatment
por: Ismail, Abdelrahman, et al.
Publicado: (2022)

Late-Stage Functionalization through Click Chemistry Provides GLUT5-Targeting Glycoconjugate as a Potential PET Imaging Probe
por: Oronova, Adelina, et al.
Publicado: (2022)

Metabolism-Driven High-Throughput Cancer Identification with GLUT5-Specific Molecular Probes
por: Kannan, Srinivas, et al.
Publicado: (2018)

Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes
por: Steinbusch, Laura K. M., et al.
Publicado: (2011)

Molecular Dynamics Simulation Studies of GLUT4: Substrate-Free and Substrate-Induced Dynamics and ATP-Mediated Glucose Transport Inhibition
por: Mohan, Suma, et al.
Publicado: (2010)

ATM and GLUT1-S490 Phosphorylation Regulate GLUT1 Mediated Transport in Skeletal Muscle
por: Andrisse, Stanley, et al.
Publicado: (2013)

Expression of the glucose transporters GLUT1, GLUT3, GLUT4 and GLUT12 in human cancer cells
por: Barron, Carly, et al.
Publicado: (2012)

Functional Expression of the Human Glucose Transporters GLUT2 and GLUT3 in Yeast Offers Novel Screening Systems for GLUT-Targeting Drugs
por: Schmidl, Sina, et al.
Publicado: (2021)

Turn-on Rhodamine Glycoconjugates Enable Real-Time GLUT Activity Monitoring in Live Cells and In Vivo
por: Soma Nyansa, Monica Mame, et al.
Publicado: (2023)

Host Adaptation Is Contingent upon the Infection Route Taken by Pathogens
por: Martins, Nelson E., et al.
Publicado: (2013)

Inhibition of human GLUT1 and GLUT5 by plant carbohydrate products; insights into transport specificity
por: George Thompson, Alayna M., et al.
Publicado: (2015)

Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism
por: Arponen, Milja, et al.
Publicado: (2022)

Transporter-Mediated Drug Delivery
por: Gyimesi, Gergely, et al.
Publicado: (2023)

Identification of Structural Determinants of the Transport of the Dehydroascorbic Acid Mediated by Glucose Transport GLUT1
por: Villagrán, Marcelo, et al.
Publicado: (2023)

Expression of GLUT1 and GLUT3 Glucose Transporters in Endometrial and Breast Cancers
por: Krzeslak, Anna, et al.
Publicado: (2012)

Structure and mechanism of the mammalian fructose transporter GLUT5
por: Nomura, Norimichi, et al.
Publicado: (2015)

Insights into Substrate and Inhibitor Selectivity among Human GLUT Transporters through Comparative Modeling and Molecular Docking
por: Ferreira, Rafaela Salgado, et al.
Publicado: (2019)

MicroRNAs-mediated regulation of glucose transporter (GLUT) expression in glioblastoma
por: Beylerli, Ozal, et al.
Publicado: (2022)

Placental expression of glucose transporters GLUT‐1, GLUT‐3, GLUT‐8 and GLUT‐12 in pregnancies complicated by gestational and type 1 diabetes mellitus
por: Stanirowski, Paweł Jan, et al.
Publicado: (2021)

Development of Glucose Transporter (GLUT) Inhibitors
por: Reckzeh, Elena S., et al.
Publicado: (2019)

GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach
por: Oliveira, Hélder, et al.
Publicado: (2019)

Conformational Studies of Glucose Transporter 1 (GLUT1) as an Anticancer Drug Target
por: Almahmoud, Suliman, et al.
Publicado: (2019)

Differential Expression of Glucose Transporter Proteins GLUT-1, GLUT-3, GLUT-8 and GLUT-12 in the Placenta of Macrosomic, Small-for-Gestational-Age and Growth-Restricted Foetuses
por: Stanirowski, Paweł Jan, et al.
Publicado: (2021)

Lipomics: A Potential Carrier for the Intravenous Delivery of Lipophilic and Hydrophilic Drugs
por: Ramírez-Hernández, David, et al.
Publicado: (2022)

Hydrophilic Natural Polylysine as Drug Nanocarrier for Preparation of Helical Delivery System
por: Yu, Bo, et al.
Publicado: (2022)

Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery
por: Huttunen, Kristiina M., et al.
Publicado: (2022)

Impact of pre-gestational and gestational diabetes mellitus on the expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 in human term placenta
por: Stanirowski, Paweł Jan, et al.
Publicado: (2016)

Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family
por: Custódio, Tânia Filipa, et al.
Publicado: (2021)

Determinants of sugar-induced influx in the mammalian fructose transporter GLUT5
por: McComas, Sarah E, et al.
Publicado: (2023)

Dyeable Hydrophilic Surface Modification for PTFE Substrates by Surface Fluorination
por: Kobayashi, Mizuki, et al.
Publicado: (2023)

Linear Decay of Retrotransposon Antisense Bias across Genes Is Contingent upon Tissue Specificity
por: Linker, Sara, et al.
Publicado: (2013)

Exacerbation of Brain Injury by Post-Stroke Exercise Is Contingent Upon Exercise Initiation Timing
por: Li, Fengwu, et al.
Publicado: (2017)

Reply: Diversity of our future workforce is contingent upon our virtual pandemic presence
por: Antonoff, Mara B.
Publicado: (2021)

Global patterns of tree density are contingent upon local determinants in the world’s natural forests
por: Madrigal-González, Jaime, et al.
Publicado: (2023)

Global Health, Geographical Contingency, and Contingent Geographies
por: Herrick, Clare
Publicado: (2016)

Osmotic Water Transport with Glucose in GLUT2 and SGLT
por: Naftalin, Richard J.
Publicado: (2008)

Immunohistochemical expression of the glucose transporters Glut-1 and Glut-3 in human malignant melanomas and benign melanocytic lesions
por: Parente, Paola, et al.
Publicado: (2008)

Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies
por: Daud, Aizati N. A., et al.
Publicado: (2017)

Development of an Optimised Application Protocol For Sonophoretic Transdermal Delivery of a Model Hydrophilic Drug
por: Sarheed, Omar, et al.
Publicado: (2011)

Combinational Delivery of Hydrophobic and Hydrophilic Anticancer Drugs in Single Nanoemulsions To Treat MDR in Cancer
por: Ma, Yan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_79kmve5qe32drc2180uq8iek9o