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Discontinuation of BRAF/MEK-Directed Targeted Therapy after Complete Remission of Metastatic Melanoma—A Retrospective Multicenter ADOReg Study
SIMPLE SUMMARY: The introduction of BRAF/MEK-directed targeted therapy (TT) has significantly improved the management of patients with advanced BRAF-V600-mutant melanoma. Although resistance occurs, there is a subgroup of patients showing a complete response (CR) to TT and who maintain durable disea...
Autores principales: | Stege, Henner, Haist, Maximilian, Schultheis, Michael, Fleischer, Maria Isabel, Mohr, Peter, Meier, Friedegund, Schadendorf, Dirk, Ugurel, Selma, Livingstone, Elisabeth, Zimmer, Lisa, Herbst, Rudolf, Pföhler, Claudia, Kähler, Katharina, Weichenthal, Michael, Terheyden, Patrick, Nashan, Dorothée, Debus, Dirk, Kaatz, Martin, Ziller, Fabian, Haferkamp, Sebastian, Forschner, Andrea, Leiter, Ulrike, Kreuter, Alexander, Ulrich, Jens, Kleemann, Johannes, Bradfisch, Fabienne, Grabbe, Stephan, Loquai, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151093/ https://www.ncbi.nlm.nih.gov/pubmed/34065877 http://dx.doi.org/10.3390/cancers13102312 |
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