Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration

Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical–biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used...

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Detalles Bibliográficos
Autor principal: Chen-Liang, Tzu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151135/
https://www.ncbi.nlm.nih.gov/pubmed/34064707
http://dx.doi.org/10.3390/jcm10102052
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author Chen-Liang, Tzu-Hua
author_facet Chen-Liang, Tzu-Hua
author_sort Chen-Liang, Tzu-Hua
collection PubMed
description Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical–biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used prognostic scoring systems and gives a general view of the prognostic impact of somatic mutations in MDS patients.
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spelling pubmed-81511352021-05-27 Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration Chen-Liang, Tzu-Hua J Clin Med Review Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical–biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used prognostic scoring systems and gives a general view of the prognostic impact of somatic mutations in MDS patients. MDPI 2021-05-11 /pmc/articles/PMC8151135/ /pubmed/34064707 http://dx.doi.org/10.3390/jcm10102052 Text en © 2021 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chen-Liang, Tzu-Hua
Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
title Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
title_full Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
title_fullStr Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
title_full_unstemmed Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
title_short Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration
title_sort prognosis in myelodysplastic syndromes: the clinical challenge of genomic integration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151135/
https://www.ncbi.nlm.nih.gov/pubmed/34064707
http://dx.doi.org/10.3390/jcm10102052
work_keys_str_mv AT chenliangtzuhua prognosisinmyelodysplasticsyndromestheclinicalchallengeofgenomicintegration

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