Cargando…

Genetic and Environmental Contributors to Neurodegeneration: An Exploration of the Effects of Alcohol on Clinical Features of Huntington’s Disease Using the Enroll-HD Global Platform

Huntington’s disease (HD) is a neurodegenerative dementia with a well recognised genetic cause. Alcohol misuse is a major environmental factor relevant to numerous neurological presentations, including HD. We explored the effects of alcohol intake on clinical features of HD by means of data from the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Symonds, Alexander L., Macerollo, Antonella, Foy, Kevin, Alusi, Sundus H., Davies, Rhys
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151139/ https://www.ncbi.nlm.nih.gov/pubmed/34065918 http://dx.doi.org/10.3390/ijerph18105113

Ejemplares similares

Enroll-HD: An Integrated Clinical Research Platform and Worldwide Observational Study for Huntington's Disease
por: Sathe, Swati, et al.
Publicado: (2021)

Exploring the predictors of financial impairment in Huntington’s disease using the Enroll-HD dataset
por: Harris, Kate L., et al.
Publicado: (2022)

Memantine Use and Cognitive Decline in Huntington's Disease: An Enroll‐HD Study
por: Ogilvie, Amy C., et al.
Publicado: (2023)

Prevalence of neurocognitive disorder in Huntington’s disease using the Enroll-HD dataset
por: Sierra, Luis A., et al.
Publicado: (2023)

Machine learning in Huntington’s disease: exploring the Enroll-HD dataset for prognosis and driving capability prediction
por: Ouwerkerk, Jasper, et al.
Publicado: (2023)

The Clinical Picture of Psychosis in Manifest Huntington's Disease: A Comprehensive Analysis of the Enroll-HD Database
por: Rocha, Natalia P., et al.
Publicado: (2018)

Antidopaminergic treatment is associated with reduced chorea and irritability but impaired cognition in Huntington’s disease (Enroll-HD)
por: Harris, Kate L, et al.
Publicado: (2020)

A Phenotypic Atlas for Huntington Disease Based on Data From the Enroll-HD Cohort Study
por: Langbehn, Douglas R., et al.
Publicado: (2023)

The relationship between non-motor features and weight-loss in the premanifest stage of Huntington’s disease
por: Khan, Wasiq, et al.
Publicado: (2021)

Understanding HD Psychosis: An Analysis from the ENROLL-HD Database
por: Jaini, Ashwin, et al.
Publicado: (2020)

Another Perspective on Huntington’s Disease: Disease Burden in Family Members and Pre-Manifest HD When Compared to Genotype-Negative Participants from ENROLL-HD
por: Achenbach, Jannis, et al.
Publicado: (2021)

Investigating Bacterial Sources of Toxicity as an Environmental Contributor to Dopaminergic Neurodegeneration
por: Caldwell, Kim A., et al.
Publicado: (2009)

Clustering and prediction of disease progression trajectories in Huntington's disease: An analysis of Enroll-HD data using a machine learning approach
por: Ko, Jinnie, et al.
Publicado: (2023)

Disease Burden of Huntington’s Disease (HD) on People Living with HD and Care Partners in Canada
por: Shaw, Eileen, et al.
Publicado: (2022)

Refining the diagnosis of Huntington disease: the PREDICT-HD study
por: Biglan, Kevin M., et al.
Publicado: (2013)

Molecule of the month: miRNA and Huntington's disease (HD)
por: Shapshak, Paul
Publicado: (2013)

To assess whether a “virtual admission” can be useful for Parkinson’s disease patients with severe motor fluctuations
por: Randall, Anna, et al.
Publicado: (2021)

Detection of Huntington’s disease decades before diagnosis: the Predict-HD study
por: Paulsen, J S, et al.
Publicado: (2008)

Compensation in Preclinical Huntington's Disease: Evidence From the Track-On HD Study
por: Klöppel, Stefan, et al.
Publicado: (2015)

Nrf2 Pathway in Huntington’s Disease (HD): What Is Its Role?
por: Tucci, Paolo, et al.
Publicado: (2022)

Glycation potentiates neurodegeneration in models of Huntington’s disease
por: Vicente Miranda, Hugo, et al.
Publicado: (2016)

Multivariate prediction of motor diagnosis in Huntington's disease: 12 years of PREDICT‐HD
por: Long, Jeffrey D., et al.
Publicado: (2015)

MicroRNAs in CSF as prodromal biomarkers for Huntington disease in the PREDICT-HD study
por: Reed, Eric R., et al.
Publicado: (2018)

Late-onset Huntington’s disease with 40–42 CAG expansion
por: Capiluppi, Elisa, et al.
Publicado: (2019)

Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington’s Disease Knock-In Mice
por: Neto, João Luís, et al.
Publicado: (2017)

Decreased Striatal RGS2 Expression Is Neuroprotective in Huntington's Disease (HD) and Exemplifies a Compensatory Aspect of HD-Induced Gene Regulation
por: Seredenina, Tamara, et al.
Publicado: (2011)

Tetrabenazine as anti-chorea therapy in Huntington Disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators
por: Frank, Samuel
Publicado: (2009)

Stem Cells for Huntington’s Disease (SC4HD): An International Consortium to Facilitate Stem Cell-Based Therapy for Huntington’s Disease
Publicado: (2021)

Volumetric Analysis of the Hypothalamus in Huntington Disease Using 3T MRI: The IMAGE-HD Study
por: Gabery, Sanaz, et al.
Publicado: (2015)

Accuracy of automated amygdala MRI segmentation approaches in Huntington's disease in the IMAGE‐HD cohort
por: Alexander, Bonnie, et al.
Publicado: (2020)

Increased Body Weight of the BAC HD Transgenic Mouse Model of Huntington’s Disease Accounts for Some but Not All of the Observed HD-like Motor Deficits
por: Kudwa, Andrea E., et al.
Publicado: (2013)

Proteostasis in striatal cells and selective neurodegeneration in Huntington’s disease
por: Margulis, Julia, et al.
Publicado: (2014)

Exposure to Environmental and Occupational Particulate Air Pollution as a Potential Contributor to Neurodegeneration and Diabetes: A Systematic Review of Epidemiological Research
por: Dimakakou, Eirini, et al.
Publicado: (2018)

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity
por: Kok, Jannigje Rachel, et al.
Publicado: (2021)

A Role for Oxidized DNA Precursors in Huntington's Disease–Like Striatal Neurodegeneration
por: De Luca, Gabriele, et al.
Publicado: (2008)

HD-PRO-TRIAD™ Validation: A Patient-reported Instrument for the Symptom Triad of Huntington's Disease
por: Carlozzi, Noelle E., et al.
Publicado: (2014)

Striatal morphology correlates with frontostriatal electrophysiological motor processing in Huntington's disease: an IMAGE‐HD study
por: Turner, Lauren M., et al.
Publicado: (2016)

Reduced amygdala volumes are related to motor and cognitive signs in Huntington's disease: The IMAGE-HD study
por: Ahveninen, Lotta M., et al.
Publicado: (2018)

Investigating longitudinal changes to frontal cortico-striatal tracts in Huntington’s disease: the IMAGE-HD study
por: Tan, Brendan, et al.
Publicado: (2022)

Full Remission of Obsessive Compulsive Disorder (OCD) Symptoms in Huntington's Disease (HD) Using Fluoxetine
por: Devasia, Mithun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_62q0b5v8rpk0c2oc0ivkphbs29