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A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells
Methods for the conversion of human induced pluripotent stem cells (hiPSCs) into motor neurons (MNs) have opened to the generation of patient-derived in vitro systems that can be exploited for MN disease modelling. However, the lack of simplified and consistent protocols and the fact that hiPSC-deri...
Autores principales: | Cutarelli, Alessandro, Martínez-Rojas, Vladimir A., Tata, Alice, Battistella, Ingrid, Rossi, Daniela, Arosio, Daniele, Musio, Carlo, Conti, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151197/ https://www.ncbi.nlm.nih.gov/pubmed/34066970 http://dx.doi.org/10.3390/cells10051127 |
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