Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors

Delivery of siRNAs for the treatment of tumors critically depends on the development of efficient nucleic acid carrier systems. The complexation of dendritic polymers (dendrimers) results in nanoparticles, called dendriplexes, that protect siRNA from degradation and mediate non-specific cellular upt...

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Detalles Bibliográficos
Autores principales: Jugel, Willi, Aigner, Achim, Michen, Susanne, Hagstotz, Alexander, Ewe, Alexander, Appelhans, Dietmar, Schackert, Gabriele, Temme, Achim, Tietze, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151203/
https://www.ncbi.nlm.nih.gov/pubmed/34066833
http://dx.doi.org/10.3390/pharmaceutics13050676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151203/
https://www.ncbi.nlm.nih.gov/pubmed/34066833
http://dx.doi.org/10.3390/pharmaceutics13050676

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