Development of Er(3+), Yb(3+) Co-Doped Y(2)O(3) NPs According to Yb(3+) Concentration by LP–PLA Method: Potential Further Biosensor

As diagnostic biosensors for analyzing fluids from the human body, the development of inorganic NPs is of increasing concern. For one, nanoceramic phosphors have been studied to meet the increasing requirements for biological, imaging, and diagnostic applications. In this study, Y(2)O(3) NPs co-doped with trivalent rare earths (erbium and ytterbium) were obtained using a liquid phase–pulsed laser ablation (LP–PLA) method after getting high density Er, Yb:Y(2)O(3) ceramic targets by Spark plasma sintering (SPS). Most NPs are under 50 nm in diameter and show high crystallinity of cubic Y(2)O(3) structure, containing (222), (440), and (332) planes via HR–TEM. Excitation under a 980 nm laser to a nanoparticle solution showed 525 and 565 nm green, and 660 nm red emissions. The green emission intensity increased and decreased with increasing Yb(3+) additive concentration, when the red spectrum continuously strengthened. Utilizing this study’s outcome, we suggest developing technology to mark invisible biomolecules dissolved in a solvent using UC luminescence of Er(3+), Yb(3+) co-doped Y(2)O(3) NPs by LP–PLA. The LP–PLA method has a potential ability for the fabrication of UC NPs for biosensors with uniform size distribution by laser parameters.