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Computational Study on Selective PDE9 Inhibitors on PDE9-Mg/Mg, PDE9-Zn/Mg, and PDE9-Zn/Zn Systems

PDE9 inhibitors have been studied to validate their potential to treat diabetes, neurodegenerative disorders, cardiovascular diseases, and erectile dysfunction. In this report, we have selected highly potent previously reported selective PDE9 inhibitors BAY73-6691R, BAY73-6691S, 28r, 28s, 3r, 3s, PF...

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Detalles Bibliográficos
Autores principales:	Sivakumar, Dakshinamurthy, Mudedla, Sathishkumar, Jang, Seonghun, Kim, Hyunjun, Park, Hyunjin, Choi, Yonwon, Oh, Joongyo, Wu, Sangwook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151263/ https://www.ncbi.nlm.nih.gov/pubmed/34068780 http://dx.doi.org/10.3390/biom11050709

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