An Integrated Approach toward NanoBRET Tracers for Analysis of GPCR Ligand Engagement

Gaining insight into the pharmacology of ligand engagement with G-protein coupled receptors (GPCRs) under biologically relevant conditions is vital to both drug discovery and basic research. NanoLuc-based bioluminescence resonance energy transfer (NanoBRET) monitoring competitive binding between flu...

Descripción completa

Detalles Bibliográficos
Autores principales: Killoran, Michael P., Levin, Sergiy, Boursier, Michelle E., Zimmerman, Kristopher, Hurst, Robin, Hall, Mary P., Machleidt, Thomas, Kirkland, Thomas A., Friedman Ohana, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151276/
https://www.ncbi.nlm.nih.gov/pubmed/34065854
http://dx.doi.org/10.3390/molecules26102857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151276/
https://www.ncbi.nlm.nih.gov/pubmed/34065854
http://dx.doi.org/10.3390/molecules26102857

Ejemplares similares