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Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

Glioma stem cells (GSCs) are tumour initiating cells which contribute to treatment resistance, temozolomide (TMZ) chemotherapy and radiotherapy, in glioblastoma (GBM), the most aggressive adult brain tumour. A major contributor to the uncontrolled tumour cell proliferation in GBM is the hyper activa...

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Detalles Bibliográficos
Autores principales:	Juric, Viktorija, Düssmann, Heiko, Lamfers, Martine L. M., Prehn, Jochen H. M., Rehm, Markus, Murphy, Brona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151379/ https://www.ncbi.nlm.nih.gov/pubmed/34066147 http://dx.doi.org/10.3390/cells10051182

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