Cargando…
Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
Muscular disorders are mainly characterized by progressive skeletal muscle weakness. There are several aspects that can be monitored, which are used to differentiate between the types of muscular disorders, ranging from the targeted muscle up to the mutated gene. An aspect that holds critical import...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151418/ https://www.ncbi.nlm.nih.gov/pubmed/34066119 http://dx.doi.org/10.3390/medicina57050488 |
_version_ | 1783698378222206976 |
---|---|
author | Bădilă, Elisabeta Lungu, Iulia Ioana Grumezescu, Alexandru Mihai Scafa Udriște, Alexandru |
author_facet | Bădilă, Elisabeta Lungu, Iulia Ioana Grumezescu, Alexandru Mihai Scafa Udriște, Alexandru |
author_sort | Bădilă, Elisabeta |
collection | PubMed |
description | Muscular disorders are mainly characterized by progressive skeletal muscle weakness. There are several aspects that can be monitored, which are used to differentiate between the types of muscular disorders, ranging from the targeted muscle up to the mutated gene. An aspect that holds critical importance when managing muscular dystrophies is that most of them exhibit cardiac abnormalities. Therefore, cardiac imaging is an essential part of muscular disorder monitoring and management. In the first section of the review, several cardiac abnormalities are introduced; afterward, different muscular dystrophies’ pathogenesis is presented. Not all muscular dystrophies necessarily present cardiac involvement; however, the ones that do are linked with the cardiac abnormalities described in the first section. Moreover, studies from the last 3 years on muscular disorders are presented alongside imaging techniques used to determine cardiac abnormalities. |
format | Online Article Text |
id | pubmed-8151418 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81514182021-05-27 Diagnosis of Cardiac Abnormalities in Muscular Dystrophies Bădilă, Elisabeta Lungu, Iulia Ioana Grumezescu, Alexandru Mihai Scafa Udriște, Alexandru Medicina (Kaunas) Review Muscular disorders are mainly characterized by progressive skeletal muscle weakness. There are several aspects that can be monitored, which are used to differentiate between the types of muscular disorders, ranging from the targeted muscle up to the mutated gene. An aspect that holds critical importance when managing muscular dystrophies is that most of them exhibit cardiac abnormalities. Therefore, cardiac imaging is an essential part of muscular disorder monitoring and management. In the first section of the review, several cardiac abnormalities are introduced; afterward, different muscular dystrophies’ pathogenesis is presented. Not all muscular dystrophies necessarily present cardiac involvement; however, the ones that do are linked with the cardiac abnormalities described in the first section. Moreover, studies from the last 3 years on muscular disorders are presented alongside imaging techniques used to determine cardiac abnormalities. MDPI 2021-05-12 /pmc/articles/PMC8151418/ /pubmed/34066119 http://dx.doi.org/10.3390/medicina57050488 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bădilă, Elisabeta Lungu, Iulia Ioana Grumezescu, Alexandru Mihai Scafa Udriște, Alexandru Diagnosis of Cardiac Abnormalities in Muscular Dystrophies |
title | Diagnosis of Cardiac Abnormalities in Muscular Dystrophies |
title_full | Diagnosis of Cardiac Abnormalities in Muscular Dystrophies |
title_fullStr | Diagnosis of Cardiac Abnormalities in Muscular Dystrophies |
title_full_unstemmed | Diagnosis of Cardiac Abnormalities in Muscular Dystrophies |
title_short | Diagnosis of Cardiac Abnormalities in Muscular Dystrophies |
title_sort | diagnosis of cardiac abnormalities in muscular dystrophies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151418/ https://www.ncbi.nlm.nih.gov/pubmed/34066119 http://dx.doi.org/10.3390/medicina57050488 |
work_keys_str_mv | AT badilaelisabeta diagnosisofcardiacabnormalitiesinmusculardystrophies AT lunguiuliaioana diagnosisofcardiacabnormalitiesinmusculardystrophies AT grumezescualexandrumihai diagnosisofcardiacabnormalitiesinmusculardystrophies AT scafaudristealexandru diagnosisofcardiacabnormalitiesinmusculardystrophies |