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Diagnosis of Cardiac Abnormalities in Muscular Dystrophies

Muscular disorders are mainly characterized by progressive skeletal muscle weakness. There are several aspects that can be monitored, which are used to differentiate between the types of muscular disorders, ranging from the targeted muscle up to the mutated gene. An aspect that holds critical import...

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Detalles Bibliográficos
Autores principales: Bădilă, Elisabeta, Lungu, Iulia Ioana, Grumezescu, Alexandru Mihai, Scafa Udriște, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151418/
https://www.ncbi.nlm.nih.gov/pubmed/34066119
http://dx.doi.org/10.3390/medicina57050488
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author Bădilă, Elisabeta
Lungu, Iulia Ioana
Grumezescu, Alexandru Mihai
Scafa Udriște, Alexandru
author_facet Bădilă, Elisabeta
Lungu, Iulia Ioana
Grumezescu, Alexandru Mihai
Scafa Udriște, Alexandru
author_sort Bădilă, Elisabeta
collection PubMed
description Muscular disorders are mainly characterized by progressive skeletal muscle weakness. There are several aspects that can be monitored, which are used to differentiate between the types of muscular disorders, ranging from the targeted muscle up to the mutated gene. An aspect that holds critical importance when managing muscular dystrophies is that most of them exhibit cardiac abnormalities. Therefore, cardiac imaging is an essential part of muscular disorder monitoring and management. In the first section of the review, several cardiac abnormalities are introduced; afterward, different muscular dystrophies’ pathogenesis is presented. Not all muscular dystrophies necessarily present cardiac involvement; however, the ones that do are linked with the cardiac abnormalities described in the first section. Moreover, studies from the last 3 years on muscular disorders are presented alongside imaging techniques used to determine cardiac abnormalities.
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spelling pubmed-81514182021-05-27 Diagnosis of Cardiac Abnormalities in Muscular Dystrophies Bădilă, Elisabeta Lungu, Iulia Ioana Grumezescu, Alexandru Mihai Scafa Udriște, Alexandru Medicina (Kaunas) Review Muscular disorders are mainly characterized by progressive skeletal muscle weakness. There are several aspects that can be monitored, which are used to differentiate between the types of muscular disorders, ranging from the targeted muscle up to the mutated gene. An aspect that holds critical importance when managing muscular dystrophies is that most of them exhibit cardiac abnormalities. Therefore, cardiac imaging is an essential part of muscular disorder monitoring and management. In the first section of the review, several cardiac abnormalities are introduced; afterward, different muscular dystrophies’ pathogenesis is presented. Not all muscular dystrophies necessarily present cardiac involvement; however, the ones that do are linked with the cardiac abnormalities described in the first section. Moreover, studies from the last 3 years on muscular disorders are presented alongside imaging techniques used to determine cardiac abnormalities. MDPI 2021-05-12 /pmc/articles/PMC8151418/ /pubmed/34066119 http://dx.doi.org/10.3390/medicina57050488 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bădilă, Elisabeta
Lungu, Iulia Ioana
Grumezescu, Alexandru Mihai
Scafa Udriște, Alexandru
Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
title Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
title_full Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
title_fullStr Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
title_full_unstemmed Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
title_short Diagnosis of Cardiac Abnormalities in Muscular Dystrophies
title_sort diagnosis of cardiac abnormalities in muscular dystrophies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151418/
https://www.ncbi.nlm.nih.gov/pubmed/34066119
http://dx.doi.org/10.3390/medicina57050488
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