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Periodontal Wound Healing and Tissue Regeneration: A Narrative Review
Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate periodontal tissues. The periodontium is a complex structure composed of specialized tissues that support the teeth, and most periodontal surgeries are invasive procedures, includi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151433/ https://www.ncbi.nlm.nih.gov/pubmed/34065862 http://dx.doi.org/10.3390/ph14050456 |
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author | Cho, Young-Dan Kim, Kyoung-Hwa Lee, Yong-Moo Ku, Young Seol, Yang-Jo |
author_facet | Cho, Young-Dan Kim, Kyoung-Hwa Lee, Yong-Moo Ku, Young Seol, Yang-Jo |
author_sort | Cho, Young-Dan |
collection | PubMed |
description | Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate periodontal tissues. The periodontium is a complex structure composed of specialized tissues that support the teeth, and most periodontal surgeries are invasive procedures, including a resection of the gingiva or the alveolar bone. The periodontal wound healing process is slightly different from cutaneous wound healing and is similar to fetal healing, being almost scar-free. The aim of this review article is to provide an overview of periodontal wound healing and discuss various surgical and pharmaceutical approaches to achieve stable wound healing and improve the treatment outcomes. In addition, detrimental and limiting factors that induce a compromised prognosis are discussed, along with the perspective and future direction for successful periodontal tissue regeneration. |
format | Online Article Text |
id | pubmed-8151433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81514332021-05-27 Periodontal Wound Healing and Tissue Regeneration: A Narrative Review Cho, Young-Dan Kim, Kyoung-Hwa Lee, Yong-Moo Ku, Young Seol, Yang-Jo Pharmaceuticals (Basel) Review Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate periodontal tissues. The periodontium is a complex structure composed of specialized tissues that support the teeth, and most periodontal surgeries are invasive procedures, including a resection of the gingiva or the alveolar bone. The periodontal wound healing process is slightly different from cutaneous wound healing and is similar to fetal healing, being almost scar-free. The aim of this review article is to provide an overview of periodontal wound healing and discuss various surgical and pharmaceutical approaches to achieve stable wound healing and improve the treatment outcomes. In addition, detrimental and limiting factors that induce a compromised prognosis are discussed, along with the perspective and future direction for successful periodontal tissue regeneration. MDPI 2021-05-12 /pmc/articles/PMC8151433/ /pubmed/34065862 http://dx.doi.org/10.3390/ph14050456 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Cho, Young-Dan Kim, Kyoung-Hwa Lee, Yong-Moo Ku, Young Seol, Yang-Jo Periodontal Wound Healing and Tissue Regeneration: A Narrative Review |
title | Periodontal Wound Healing and Tissue Regeneration: A Narrative Review |
title_full | Periodontal Wound Healing and Tissue Regeneration: A Narrative Review |
title_fullStr | Periodontal Wound Healing and Tissue Regeneration: A Narrative Review |
title_full_unstemmed | Periodontal Wound Healing and Tissue Regeneration: A Narrative Review |
title_short | Periodontal Wound Healing and Tissue Regeneration: A Narrative Review |
title_sort | periodontal wound healing and tissue regeneration: a narrative review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151433/ https://www.ncbi.nlm.nih.gov/pubmed/34065862 http://dx.doi.org/10.3390/ph14050456 |
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