Cargando…
The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer’s Disease
The development of Alzheimer’s disease (AD) is influenced by several events, among which the dysregulation of cholesterol metabolism in the brain plays a major role. Maintenance of brain cholesterol homeostasis is essential for neuronal functioning and brain development. To maintain the steady-state...
Autores principales: | Gamba, Paola, Giannelli, Serena, Staurenghi, Erica, Testa, Gabriella, Sottero, Barbara, Biasi, Fiorella, Poli, Giuseppe, Leonarduzzi, Gabriella |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151638/ https://www.ncbi.nlm.nih.gov/pubmed/34067119 http://dx.doi.org/10.3390/antiox10050740 |
Ejemplares similares
-
24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer’s Disease
por: Testa, Gabriella, et al.
Publicado: (2023) -
Cholesterol Dysmetabolism in Alzheimer’s Disease: A Starring Role for Astrocytes?
por: Staurenghi, Erica, et al.
Publicado: (2021) -
A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer’s Disease
por: Gamba, Paola, et al.
Publicado: (2019) -
A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1
por: Testa, Gabriella, et al.
Publicado: (2018) -
Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability
por: Gargiulo, Simona, et al.
Publicado: (2015)