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Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms

In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible t...

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Detalles Bibliográficos
Autores principales: Farkas, Dóra, Madarász, Lajos, Nagy, Zsombor K., Antal, István, Kállai-Szabó, Nikolett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151645/
https://www.ncbi.nlm.nih.gov/pubmed/34068724
http://dx.doi.org/10.3390/pharmaceutics13050685
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author Farkas, Dóra
Madarász, Lajos
Nagy, Zsombor K.
Antal, István
Kállai-Szabó, Nikolett
author_facet Farkas, Dóra
Madarász, Lajos
Nagy, Zsombor K.
Antal, István
Kállai-Szabó, Nikolett
author_sort Farkas, Dóra
collection PubMed
description In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible to take images of various pharmaceutical dosage forms with different imaging methods in a size range that is hardly visible or completely invisible to the human eye. By analyzing high-quality designs, physicochemical processes can be understood, and the results can be used even in the optimization of the composition of the dosage form and in the development of its production. The present study aims to show some of the countless ways image analysis can be used in the manufacturing and quality assessment of different dosage forms. This summary also includes measurements and an evaluation of, amongst others, a less studied dosage form, medicated foams.
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spelling pubmed-81516452021-05-27 Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms Farkas, Dóra Madarász, Lajos Nagy, Zsombor K. Antal, István Kállai-Szabó, Nikolett Pharmaceutics Review In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible to take images of various pharmaceutical dosage forms with different imaging methods in a size range that is hardly visible or completely invisible to the human eye. By analyzing high-quality designs, physicochemical processes can be understood, and the results can be used even in the optimization of the composition of the dosage form and in the development of its production. The present study aims to show some of the countless ways image analysis can be used in the manufacturing and quality assessment of different dosage forms. This summary also includes measurements and an evaluation of, amongst others, a less studied dosage form, medicated foams. MDPI 2021-05-10 /pmc/articles/PMC8151645/ /pubmed/34068724 http://dx.doi.org/10.3390/pharmaceutics13050685 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Farkas, Dóra
Madarász, Lajos
Nagy, Zsombor K.
Antal, István
Kállai-Szabó, Nikolett
Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
title Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
title_full Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
title_fullStr Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
title_full_unstemmed Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
title_short Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
title_sort image analysis: a versatile tool in the manufacturing and quality control of pharmaceutical dosage forms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151645/
https://www.ncbi.nlm.nih.gov/pubmed/34068724
http://dx.doi.org/10.3390/pharmaceutics13050685
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