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Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151645/ https://www.ncbi.nlm.nih.gov/pubmed/34068724 http://dx.doi.org/10.3390/pharmaceutics13050685 |
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author | Farkas, Dóra Madarász, Lajos Nagy, Zsombor K. Antal, István Kállai-Szabó, Nikolett |
author_facet | Farkas, Dóra Madarász, Lajos Nagy, Zsombor K. Antal, István Kállai-Szabó, Nikolett |
author_sort | Farkas, Dóra |
collection | PubMed |
description | In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible to take images of various pharmaceutical dosage forms with different imaging methods in a size range that is hardly visible or completely invisible to the human eye. By analyzing high-quality designs, physicochemical processes can be understood, and the results can be used even in the optimization of the composition of the dosage form and in the development of its production. The present study aims to show some of the countless ways image analysis can be used in the manufacturing and quality assessment of different dosage forms. This summary also includes measurements and an evaluation of, amongst others, a less studied dosage form, medicated foams. |
format | Online Article Text |
id | pubmed-8151645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81516452021-05-27 Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms Farkas, Dóra Madarász, Lajos Nagy, Zsombor K. Antal, István Kállai-Szabó, Nikolett Pharmaceutics Review In pharmaceutical sciences, visual inspection is one of the oldest methods used for description in pharmacopeias and is still an important part of the characterization and qualification of active ingredients, excipients, and dosage forms. With the development of technology, it is now also possible to take images of various pharmaceutical dosage forms with different imaging methods in a size range that is hardly visible or completely invisible to the human eye. By analyzing high-quality designs, physicochemical processes can be understood, and the results can be used even in the optimization of the composition of the dosage form and in the development of its production. The present study aims to show some of the countless ways image analysis can be used in the manufacturing and quality assessment of different dosage forms. This summary also includes measurements and an evaluation of, amongst others, a less studied dosage form, medicated foams. MDPI 2021-05-10 /pmc/articles/PMC8151645/ /pubmed/34068724 http://dx.doi.org/10.3390/pharmaceutics13050685 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Farkas, Dóra Madarász, Lajos Nagy, Zsombor K. Antal, István Kállai-Szabó, Nikolett Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms |
title | Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms |
title_full | Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms |
title_fullStr | Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms |
title_full_unstemmed | Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms |
title_short | Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms |
title_sort | image analysis: a versatile tool in the manufacturing and quality control of pharmaceutical dosage forms |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151645/ https://www.ncbi.nlm.nih.gov/pubmed/34068724 http://dx.doi.org/10.3390/pharmaceutics13050685 |
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