Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

Compounds bearing thiazole and chalcone pharmacophores have been reported to possess excellent antitubercular and anticancer activities. In view of this, we designed, synthesized and characterized a novel series of thiazole–chalcone hybrids (1–20) and further evaluated them for antitubercular and an...

Descripción completa

Detalles Bibliográficos
Autores principales: Kasetti, Ashok Babu, Singhvi, Indrajeet, Nagasuri, Ravindra, Bhandare, Richie R., Shaik, Afzal B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151732/
https://www.ncbi.nlm.nih.gov/pubmed/34064806
http://dx.doi.org/10.3390/molecules26102847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151732/
https://www.ncbi.nlm.nih.gov/pubmed/34064806
http://dx.doi.org/10.3390/molecules26102847

Ejemplares similares