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Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation
Compounds bearing thiazole and chalcone pharmacophores have been reported to possess excellent antitubercular and anticancer activities. In view of this, we designed, synthesized and characterized a novel series of thiazole–chalcone hybrids (1–20) and further evaluated them for antitubercular and an...
Autores principales: | Kasetti, Ashok Babu, Singhvi, Indrajeet, Nagasuri, Ravindra, Bhandare, Richie R., Shaik, Afzal B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151732/ https://www.ncbi.nlm.nih.gov/pubmed/34064806 http://dx.doi.org/10.3390/molecules26102847 |
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