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Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications
The number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue or areas of interest. MRS has been applied in b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151733/ https://www.ncbi.nlm.nih.gov/pubmed/34067193 http://dx.doi.org/10.3390/diagnostics11050842 |
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author | Pasanta, Duanghathai Htun, Khin Thandar Pan, Jie Tungjai, Montree Kaewjaeng, Siriprapa Kim, Hongjoo Kaewkhao, Jakrapong Kothan, Suchart |
author_facet | Pasanta, Duanghathai Htun, Khin Thandar Pan, Jie Tungjai, Montree Kaewjaeng, Siriprapa Kim, Hongjoo Kaewkhao, Jakrapong Kothan, Suchart |
author_sort | Pasanta, Duanghathai |
collection | PubMed |
description | The number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue or areas of interest. MRS has been applied in both research and clinical studies to assess liver fat noninvasively in vivo. MRS has also demonstrated excellent performance in liver fat assessment with high sensitivity and specificity compared to biopsy and other imaging modalities. Because of these qualities, MRS has been generally accepted as the reference standard for the noninvasive measurement of liver steatosis. MRS is an evolving technique with high potential as a diagnostic tool in the clinical setting. This review aims to provide a brief overview of the MRS principle for liver fat assessment and its application, and to summarize the current state of MRS study in comparison to other techniques. |
format | Online Article Text |
id | pubmed-8151733 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81517332021-05-27 Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications Pasanta, Duanghathai Htun, Khin Thandar Pan, Jie Tungjai, Montree Kaewjaeng, Siriprapa Kim, Hongjoo Kaewkhao, Jakrapong Kothan, Suchart Diagnostics (Basel) Review The number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue or areas of interest. MRS has been applied in both research and clinical studies to assess liver fat noninvasively in vivo. MRS has also demonstrated excellent performance in liver fat assessment with high sensitivity and specificity compared to biopsy and other imaging modalities. Because of these qualities, MRS has been generally accepted as the reference standard for the noninvasive measurement of liver steatosis. MRS is an evolving technique with high potential as a diagnostic tool in the clinical setting. This review aims to provide a brief overview of the MRS principle for liver fat assessment and its application, and to summarize the current state of MRS study in comparison to other techniques. MDPI 2021-05-07 /pmc/articles/PMC8151733/ /pubmed/34067193 http://dx.doi.org/10.3390/diagnostics11050842 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pasanta, Duanghathai Htun, Khin Thandar Pan, Jie Tungjai, Montree Kaewjaeng, Siriprapa Kim, Hongjoo Kaewkhao, Jakrapong Kothan, Suchart Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
title | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
title_full | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
title_fullStr | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
title_full_unstemmed | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
title_short | Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications |
title_sort | magnetic resonance spectroscopy of hepatic fat from fundamental to clinical applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151733/ https://www.ncbi.nlm.nih.gov/pubmed/34067193 http://dx.doi.org/10.3390/diagnostics11050842 |
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