Cargando…

Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular weight, through differently prepared hydrogels....

Descripción completa

Detalles Bibliográficos
Autores principales:	Teaima, Mahmoud H., Mohamed, Mohamed Azmi Ahmed, Abd El Rehem, Randa Tag, Tayel, Saadia A., El-Nabarawi, Mohamed A., Fouad, Shahinaze A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151755/ https://www.ncbi.nlm.nih.gov/pubmed/34068544 http://dx.doi.org/10.3390/pharmaceutics13050682

Ejemplares similares

Transdermal Delivery of Telmisartan: Formulation, in vitro, ex vivo, Iontophoretic Permeation Enhancement and Comparative Pharmacokinetic Study in Rats
por: Teaima, Mahmoud, et al.
Publicado: (2021)

Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies
por: Fahmy, Abdurrahman M., et al.
Publicado: (2017)

Tailoring of PEGylated bilosomes for promoting the transdermal delivery of olmesartan medoxomil: in-vitro characterization, ex-vivo permeation and in-vivo assessment
por: Albash, Rofida, et al.
Publicado: (2019)

Influence of Chemical Enhancers and Iontophoresis on the In Vitro Transdermal Permeation of Propranolol: Evaluation by Dermatopharmacokinetics
por: Calatayud-Pascual, María Aracely, et al.
Publicado: (2018)

Use of transethosomes for enhancing the transdermal delivery of olmesartan medoxomil: in vitro, ex vivo, and in vivo evaluation
por: Albash, Rofida, et al.
Publicado: (2019)

Optimization of hyaluronan-enriched cubosomes for bromfenac delivery enhancing corneal permeation: characterization, ex vivo, and in vivo evaluation
por: Shoman, Nabil A., et al.
Publicado: (2023)

Compritol-Based Nanostrucutured Lipid Carriers (NLCs) for Augmentation of Zolmitriptan Bioavailability via the Transdermal Route: In Vitro Optimization, Ex Vivo Permeation, In Vivo Pharmacokinetic Study
por: Hassan, Doaa H., et al.
Publicado: (2022)

Unroasted Green Coffee Extract-Loaded Solid Lipid Nanoparticles for Enhancing Intestinal Permeation
por: Moussa, Yomna A., et al.
Publicado: (2023)

Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation
por: Fouad, Shahinaze A., et al.
Publicado: (2020)

Enhanced Ocular Anti-Aspergillus Activity of Tolnaftate Employing Novel Cosolvent-Modified Spanlastics: Formulation, Statistical Optimization, Kill Kinetics, Ex Vivo Trans-Corneal Permeation, In Vivo Histopathological and Susceptibility Study
por: Aziz, Diana, et al.
Publicado: (2022)

Biophysical assessment of DC iontophoresis and current density on transdermal permeation of methotrexate
por: Prasad, Rachna, et al.
Publicado: (2011)

Implementing polymeric pseudorotaxanes for boosting corneal permeability and antiaspergillus activity of tolnaftate: formulation development, statistical optimization, ex vivo permeation and in vivo assessment
por: Aziz, Diana, et al.
Publicado: (2022)

Enhanced Transdermal Delivery of Granisetron by Using Iontophoresis
por: Panzade, Prabhakar, et al.
Publicado: (2012)

Transdermal Delivery by Iontophoresis
por: Rawat, Swati, et al.
Publicado: (2008)

Sertaconazole-Nitrate-Loaded Leciplex for Treating Keratomycosis: Optimization Using D-Optimal Design and In Vitro, Ex Vivo, and In Vivo Studies
por: Abdellatif, Menna M., et al.
Publicado: (2022)

Formulation of novel niosomal repaglinide chewable tablets using coprocessed excipients: in vitro characterization, optimization and enhanced hypoglycemic activity in rats
por: Fouad, Shahinaze A., et al.
Publicado: (2023)

Transdermal iontophoresis delivery system for terazosin hydrochloride: an in vitro and in vivo study
por: Jiang, Changzhao, et al.
Publicado: (2021)

Proniosomal Telmisartan Tablets: Formulation, in vitro Evaluation and in vivo Comparative Pharmacokinetic Study in Rabbits
por: Teaima, Mahmoud Hasan, et al.
Publicado: (2020)

Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation
por: Teaima, Mahmoud H., et al.
Publicado: (2022)

Liver Targeting of Daclatasvir via Tailoring Sterically Stabilized Bilosomes: Fabrication, Comparative In Vitro/In Vivo Appraisal and Biodistribution Studies
por: El-Nabarawi, Mohamed, et al.
Publicado: (2021)

Bilosomes as Promising Nanovesicular Carriers for Improved Transdermal Delivery: Construction, in vitro Optimization, ex vivo Permeation and in vivo Evaluation
por: Ahmed, Sadek, et al.
Publicado: (2020)

Formulation and Evaluation of Transdermal Gel Containing Tacrolimus-Loaded Spanlastics: In Vitro, Ex Vivo and In Vivo Studies
por: Zaki, Randa Mohammed, et al.
Publicado: (2022)

Transdermal iontophoresis patch with reverse electrodialysis
por: Lee, Joon, et al.
Publicado: (2017)

Construction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization and In vivo clinical comparative pharmacokinetic study in healthy human subjects
por: Teaima, Mahmoud, et al.
Publicado: (2022)

Ion-Triggered In Situ Gelling Intranasal Spray of Dronedarone Hydrochloride Nanocarriers: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal
por: Teaima, Mahmoud H., et al.
Publicado: (2022)

Formulation and Characterization of Acetazolamide/Carvedilol Niosomal Gel for Glaucoma Treatment: In Vitro, and In Vivo Study
por: Abdelmonem, Rehab, et al.
Publicado: (2021)

Fabrication of Ethosomes Containing Tocopherol Acetate to Enhance Transdermal Permeation: In Vitro and Ex Vivo Characterizations
por: Akhtar, Naheed, et al.
Publicado: (2022)

Preparation of solid dispersion systems for enhanced dissolution of poorly water soluble diacerein: In-vitro evaluation, optimization and physiologically based pharmacokinetic modeling
por: Fouad, Shahinaze A., et al.
Publicado: (2021)

Transdermal Delivery of Capsaicin Nanoemulgel: Optimization, Skin Permeation and In Vivo Activity against Diabetic Neuropathy
por: Saab, May, et al.
Publicado: (2022)

Promising Swellable Floating Bupropion Tablets: Formulation, in vitro/in vivo Evaluation and Comparative Pharmacokinetic Study in Human Volunteers
por: Teaima, Mahmoud, et al.
Publicado: (2020)

Bisoprolol Transdermal Patch Is Effective for the Treatment of AF Tachycardia
por: Arita, Yoh, et al.
Publicado: (2018)

Effect of Chemical Enhancers in Transdermal Permeation of Alfuzosin Hydrochloride
por: Prasanthi, D., et al.
Publicado: (2012)

Enhanced transdermal insulin basal release from silk fibroin (SF) hydrogels via iontophoresis
por: Sakunpongpitiporn, Phimchanok, et al.
Publicado: (2022)

Use of electroporation and reverse iontophoresis for extraction of transdermal multibiomarkers
por: Ching, Congo Tak-Shing, et al.
Publicado: (2012)

Aliskiren Hemifumarate Proliposomes for Improved Oral Drug Delivery: Formulation Development, In Vitro and In Vivo Permeability Testing
por: Kunamaneni, Priyanka, et al.
Publicado: (2022)

Etodolac transdermal cubosomes for the treatment of rheumatoid arthritis: ex vivo permeation and in vivo pharmacokinetic studies
por: Salah, Salwa, et al.
Publicado: (2017)

Development and evaluation of fixed dose bi therapy sublingual tablets for treatment stress hypertension and anxiety
por: El-Nabarawi, Mohamed A., et al.
Publicado: (2013)

N-Alkylmorpholines: Potent Dermal and Transdermal Skin Permeation Enhancers
por: Dvořáková, Kristýna, et al.
Publicado: (2021)

Transdermal Permeation Assays of Curcumin Aided by CAGE-IL: In Vivo Control of Psoriasis
por: Boscariol, Rodrigo, et al.
Publicado: (2022)

Simultaneous, noninvasive, and transdermal extraction of urea and homocysteine by reverse iontophoresis
por: Ching, Congo Tak-Shing, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_rbhaa012ec4k2lo96bbeb51sh6